Mediators of endoplasmic reticulum stress‐induced apoptosis
نویسندگان
چکیده
منابع مشابه
Mediators of endoplasmic reticulum stress-induced apoptosis.
The efficient functioning of the endoplasmic reticulum (ER) is essential for most cellular activities and survival. Conditions that interfere with ER function lead to the accumulation and aggregation of unfolded proteins. ER transmembrane receptors detect the onset of ER stress and initiate the unfolded protein response (UPR) to restore normal ER function. If the stress is prolonged, or the ada...
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ژورنال
عنوان ژورنال: EMBO reports
سال: 2006
ISSN: 1469-221X,1469-3178
DOI: 10.1038/sj.embor.7400779